Obesity and diabetes

Obesity is a condition that a person has accumulated much body fat, which it might have a negative impact on one’s health. Being obese significantly increases the risk of developing type 2 diabetes and high blood pressure, and these conditions are associated with heart diseases. Both diabetes and obesity are becoming a problem globally. Obesity can lead to fat deposits all over the body. Fat inhibits the cell’s ability to absorb and use glucose, which leads to the body developing insulin resistance. As a result, blood sugar levels increase, and the patient develops Type 2 diabetes. Insulin is a vital hormone in the body that controls the amount of glucose in the bloodstream. The pancreas, which is the organ responsible for producing it. Insulin converts the sugar in the body into energy, which is then used by the body cells to perform various functions. Type 2 diabetes mellitus is characterized by hyper-glycemia, insulin resistance, and relative impairment in insulin secretion and its possible long-term complications. Insulin resistance is determined by genetic factors or environmental factors, for example, saturated and trans-fat high diet, obesity, and aging. However, researchers have established a strong link between pre-diabetes and obesity. They state that obese children are 4 times more likely than other children to develop diabetes by the time they reach 25 years of age.

Obesity impacts three different body mechanisms, which lead to the development of diabetes. First, it helps increase the production of cytokines, tumor necrosis factor-A, and retinol-binding protein. All of these contribute to insulin resistance. Second, it leads to mitochondrial dysfunction, which decreases the body’s sensitivity to insulin. Third, it leads to ectopic fat deposits in the liver and skeletal muscle, which leads to diabetes. Stay safe.

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